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Space travel accelerates human failure: HSPC aging and new findings

samparker by samparker
September 8, 2025
in Science & Space
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There is a clear fact that space travels forced its boundaries to the human body. These journeys bring about stress factors such as micro gravity, high radiation levels and long -term insulation; This can affect health in various ways. Scientists are conducting intensive studies to understand these effects. A new research offers clues about another aspect of health in space. Hematopoietic root and progenitor cells, called HSPC, are critical cells that form the basis of the blood and immune system, and have underlined how space flight affects these cells.

Findings show that space journey reduces the capacity of HSPCs and the ability to produce new healthy cells over time. Although the cells seem unexpectedly more activated, they quickly consume their energy warehouses and lose their rest and recovery capacity. Over time, regeneration difficulties emerge and new cell production decreases. In addition, DNA damage, shortening telomerers and inflammation in mitochondria also draw attention.

The study reveals that it is an effort for a stable situation by activating the hidden areas of the genomes of some cells. These results indicate that space can quickly age the human body and provide a picture that those who aim for longer life in the future should not think of being in space.

Developed within the framework of NASA and Space Tango partnership, the mini biosensor -based nanobirator platform is watching human stem cells in challenging conditions of the spot and watching human stem cells and artificial intelligence -supported imaging. The system was sent to the International Space Station (ISS) with a SpaceX supply task and during 32 to 45 days of office, significant aging signs appeared in HSPCs. Priority as the cells were working more intensively, energy consumed quickly and lost their recreation healing capacity. This process began to reduce rejuvenation and reproduction capacity.

As a result, space travels can quickly age the human body. For those who plan to stay in space for longer periods in the future, these findings create a critical basis for assessing risks.

Tags: Astronaut HealthDNA damagehematopoietic stem cellsHSPC agingISSMicro Gravity HealthNanobiractorNASA Space TangoSpace Healthspace travel effectstelomer length

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